Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571648 | 0.86 | TSHR (0.41) | FAAHLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL4414999 | 0.84 | ALDH1A1 (0.53) | ALDH1A1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL7573224 | 0.82 | CNR2 (0.58) | ALDH1A1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL6136640 | 0.80 | ALDH1A1 (0.57) | ALDH1A1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL7569870 | 0.80 | TDP1 (0.58) | ALDH1A1FAAHRAB9ALMNAKMT2A | |
| SCHEMBL7574286 | 0.80 | CNR2 (0.46) | FAAHTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL7567337 | 0.78 | ELANE (0.48) | KMT2AMEN1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL21659413 | 0.77 | L3MBTL1 (0.50) | ALDH1A1FAAHKMT2AMEN1L3MBTL1 | |
| SCHEMBL7570560 | 0.77 | KMT2A (0.47) | ALDH1A1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL7567608 | 0.76 | CASP1 (0.44) | ALDH1A1RAB9AKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |