Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569870 | 0.86 | TDP1 (0.58) | CNR2TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7573224 | 0.86 | CNR2 (0.58) | CNR2TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7571824 | 0.86 | EPHX2 (0.51) | EPHX2FAAH | |
| SCHEMBL7571045 | 0.86 | GLS (0.45) | CNR2EPHX2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7573699 | 0.85 | FAAH (0.50) | FFAR2KDM4ECYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL4417086 | 0.84 | CNR2 (0.47) | CNR2TDP1SRCFFAR2KDM4E | |
| SCHEMBL7567337 | 0.82 | ELANE (0.48) | CNR2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL7570691 | 0.82 | SMN1; SMN2 (0.50) | TDP1CYP2D6SMN1; SMN2MAOB | |
| SCHEMBL6136575 | 0.81 | CNR2 (0.57) | CNR2TDP1SRCFFAR2KDM4E | |
| SCHEMBL7576535 | 0.80 | ALDH1A1 (0.49) | TDP1KDM4ESMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |