Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313134 | 0.88 | CYP1A2 (0.61) | KCNH2DRD2DRD3PTK2HTR1A | |
| SCHEMBL9275980 | 0.70 | HTR1A (0.57) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL9053380 | 0.70 | CYP2D6 (0.43) | KCNH2HTR1AHTR1DHTR1BLMNA | |
| SCHEMBL6305611 | 0.68 | HTR1A (0.48) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL21180000 | 0.67 | KIF11 (0.62) | KCNH2CYP1A2CYP3A4CLK4LMNA | |
| SCHEMBL6308342 | 0.67 | CHRM1 (0.62) | MEN1KMT2ACYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL21092440 | 0.66 | KIF11 (0.69) | CYP1A2CYP3A4CLK4LMNAMAPK1 | |
| SCHEMBL28843821 | 0.65 | DRD2 (0.56) | KCNH2DRD2DRD3PTK2HTR1A | |
| SCHEMBL22823902 | 0.65 | GRIA2 (0.69) | KCNH2CYP1A2CYP3A4CLK4LMNA | |
| SCHEMBL7179130 | 0.65 | KIF11 (0.68) | CYP1A2CYP3A4LMNAALDH1A1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058811-A1 | Naphthalene derivatives | CHENARD BERTRAND L (US) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058811-A1 | Naphthalene derivatives | HTR4, CNR1, CNR2 | KCNH2 304/4885DRD2 121/4885DRD3 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.