Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054002 | 0.92 | DRD2 (0.51) | HTR1AHTR1DHTR1BLMNAMAPT | |
| SCHEMBL6308342 | 0.84 | CHRM1 (0.62) | CYP2D6CYP2C9CHRM1CHRM5CHRM3 | |
| SCHEMBL8077724 | 0.77 | L3MBTL1 (0.39) | KDM1AADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL6305703 | 0.76 | CHRM1 (0.53) | CHRM1CHRM5HTR1AHTR1DHTR1B | |
| SCHEMBL9275980 | 0.74 | HTR1A (0.57) | CYP2D6HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL6308077 | 0.72 | HTR1A (0.53) | CHRM1HTR1AHTR1DHTR1BLMNA | |
| SCHEMBL6308232 | 0.70 | RAB9A (0.55) | HTR1AHTR1DHTR1BLMNAMAPT | |
| SCHEMBL7568458 | 0.70 | KCNH2 (0.49) | CYP2D6CYP2C9KDM1AHTR1AHTR1D | |
| SCHEMBL6418686 | 0.69 | HTR1A (0.64) | CYP2D6HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9052843 | 0.68 | HTR1A (0.49) | CYP2D6HTR6HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |