Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.53 |
| ▸ | ACLY | P53396 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 4/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567742 | 0.87 | CCR2 (0.64) | CCR2HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7574296 | 0.85 | ALDH1A1 (0.46) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7568102 | 0.84 | PTPN2 (0.52) | CCR2HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7567262 | 0.84 | CCR2 (0.55) | CCR2HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7567292 | 0.84 | HSPD1 (0.51) | CCR2HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7571744 | 0.83 | HSPD1 (0.52) | CCR2HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7568150 | 0.82 | HSPD1 (0.51) | CCR2HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7590087 | 0.81 | GSK3B (0.44) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7571988 | 0.80 | ACLY (0.48) | CCR2ACLYIDH2IDH1PTGES2 | |
| SCHEMBL7595317 | 0.77 | ACLY (0.40) | HSPD1PTPN2PTPN1PTPN5HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |