Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 2/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567262 | 0.91 | CCR2 (0.55) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7573750 | 0.88 | ACLY (0.56) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7567742 | 0.84 | CCR2 (0.64) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7568102 | 0.84 | PTPN2 (0.52) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7567292 | 0.83 | HSPD1 (0.51) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7588736 | 0.83 | CCR9 (0.45) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7572091 | 0.83 | CCR2 (0.54) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7573695 | 0.81 | HSPD1 (0.49) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7568150 | 0.81 | HSPD1 (0.51) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL7566450 | 0.76 | PGAM1 (0.51) | HSPD1PTPN2PTPN1PTPN5HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |