Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 2/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690504 | 0.83 | ALDH1A1 (0.54) | HTR7TAAR1TRPM5ALDH1A1HPGD | |
| SCHEMBL10295512 | 0.70 | HTR2A (0.40) | CYP11B1CYP11B2TAAR1TRPM5ALDH1A1 | |
| SCHEMBL6027535 | 0.69 | CHRM2 (0.47) | ALDH1A1MEN1ALOX15KMT2AGAA | |
| SCHEMBL28230641 | 0.66 | HTR7 (0.80) | CYP11B1CYP11B2HTR7 | |
| SCHEMBL18176030 | 0.66 | HTR7 (0.46) | CYP11B1CYP11B2HTR7ALOX15KMT2A | |
| SCHEMBL9501323 | 0.65 | ALDH1A1 (0.58) | TAAR1TRPM5ALDH1A1MEN1USP2 | |
| SCHEMBL4074911 | 0.65 | DHPS (0.59) | DHPSHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14927056 | 0.63 | KCNA5 (0.50) | CYP11B1CYP11B2KCNA5KCNH2TNF | |
| SCHEMBL1111683 | 0.63 | HTR7 (0.64) | CYP11B1CYP11B2HTR7 | |
| SCHEMBL30108234 | 0.63 | HTR7 (0.69) | HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072547-A1 | AMINATION PROCESS | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2002-09-19 | — | — | WO | disclosed |
| WO-2002070439-A2 | AMINATION PROCESS | JOHNSTON, JEFFREY, N. | 2002-09-12 | — | — | WO | disclosed |