Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.61 |
| ▸ | RAB9A | P51151 | 10/20 | 0.61 |
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574989 | 0.87 | RAB9A (0.61) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL7573984 | 0.79 | CRHBP (0.50) | MAPTMAPK1ALDH1A1 | |
| SCHEMBL7576552 | 0.77 | MEN1 (0.51) | MAPTRAB9ANPC1MAPK1PKM | |
| SCHEMBL6716665 | 0.77 | SMN1; SMN2 (0.56) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL11355262 | 0.77 | MAPT (0.63) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL6716681 | 0.77 | SMN1; SMN2 (0.55) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL11295618 | 0.75 | MAPT (0.68) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL7165979 | 0.74 | PKM (0.63) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL15063512 | 0.74 | PKM (0.80) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL6716670 | 0.74 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |