Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571115 | 0.86 | KMT2A (0.54) | CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2 | |
| SCHEMBL7573224 | 0.86 | CNR2 (0.58) | GLSCYP1A2CYP2D6KDM4EPDE4A | |
| SCHEMBL7574286 | 0.86 | CNR2 (0.46) | GLSCYP1A2CYP2D6KDM4EPDE4A | |
| SCHEMBL7571824 | 0.86 | EPHX2 (0.51) | EPHX2ALDH1A1POLB | |
| SCHEMBL4420678 | 0.84 | ALDH1A1 (0.44) | GLSEGFRERBB2ALDH1A1POLB | |
| SCHEMBL7573699 | 0.83 | FAAH (0.50) | CYP1A2CYP2D6KDM4ESMN1; SMN2MAOB | |
| SCHEMBL7567337 | 0.82 | ELANE (0.48) | CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2 | |
| SCHEMBL7570691 | 0.82 | SMN1; SMN2 (0.50) | CYP2D6SMN1; SMN2MAOBALDH1A1MAPT | |
| SCHEMBL6136809 | 0.81 | EGFR (0.52) | GLSCNR2EGFRERBB2POLB | |
| SCHEMBL8599743 | 0.80 | CA2 (0.46) | CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |