Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TCF4 | P15884 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570489 | 0.87 | LMNA (0.52) | KDM4ESMN1; SMN2ALDH1A1TSHRNPSR1 | |
| SCHEMBL1126923 | 0.80 | LMNA (0.54) | ACLYKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7569777 | 0.80 | CYP2C9 (0.64) | CYP2C9KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL1726830 | 0.78 | ACLY (0.56) | ACLYKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1127264 | 0.77 | FFAR4 (0.50) | KDM4ESMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL30464235 | 0.77 | FFAR4 (0.50) | KDM4ESMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL7593482 | 0.76 | SLC40A1 (0.57) | POLBCCR2PKMLMNASLC40A1 | |
| SCHEMBL3237044 | 0.76 | KDM4E (0.77) | CYP2C9KDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL7567314 | 0.76 | NPSR1 (0.59) | ACLYCYP2C9ALDH1A1NPSR1CCR2 | |
| SCHEMBL22146044 | 0.75 | ALPL (0.56) | POLBTCF4CTNNB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |