Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 11/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582068 | 0.85 | ULK1 (0.54) | ULK1ALDH1A1MAPTHDAC1NPC1 | |
| SCHEMBL7577550 | 0.82 | PPARG (0.51) | ULK1ALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL7574119 | 0.82 | ALDH1A1 (0.56) | ULK1ALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL2484664 | 0.81 | GAA (0.50) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL16664407 | 0.81 | GAA (0.50) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13241014 | 0.81 | GAA (0.50) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2486567 | 0.80 | GAA (0.49) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7576884 | 0.77 | ALDH1A1 (0.43) | ULK1ALDH1A1NPC1 | |
| SCHEMBL12071889 | 0.76 | ULK1 (0.47) | ULK1ALDH1A1MAPTHDAC1NPC1 | |
| SCHEMBL2483532 | 0.76 | ULK1 (0.47) | ULK1ALDH1A1MAPTHDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |