Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582068 | 0.85 | ULK1 (0.54) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL7583928 | 0.85 | TAS1R3 (0.51) | RAB9ANPC1KMT2AMEN1TAS1R3 | |
| SCHEMBL3216199 | 0.84 | MEN1 (0.48) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7578428 | 0.82 | MAP2K1 (0.44) | RAB9ASMN1; SMN2NPC1ULK1ALDH1A1 | |
| SCHEMBL7574119 | 0.82 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2NPC1HPGDKMT2A | |
| SCHEMBL7577574 | 0.82 | MEN1 (0.48) | RAB9ASMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL16664407 | 0.81 | GAA (0.50) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL2484664 | 0.81 | GAA (0.50) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL13241014 | 0.81 | GAA (0.50) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL7575575 | 0.81 | KCNMA1 (0.54) | RAB9ASMN1; SMN2NPC1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |