Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7578041 | 0.84 | ALDH1A1 (0.60) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7576014 | 0.84 | SMN1; SMN2 (0.60) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28839565 | 0.83 | LMNA (0.55) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7582055 | 0.82 | RAB9A (0.51) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7576130 | 0.79 | NPC1 (0.56) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7574185 | 0.77 | HPGD (0.57) | LMNAMEN1KMT2AMAPTCA1 | |
| SCHEMBL5244119 | 0.77 | MEN1 (0.68) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7582132 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL7585239 | 0.76 | KMT2A (0.57) | LMNAMEN1KMT2AMAPTHTT | |
| SCHEMBL7584383 | 0.76 | ALOX5 (0.50) | MEN1KMT2AMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |