Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ACLY | P53396 | 3/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CDK7 | P50613 | 1/20 | 0.55 |
| ▸ | CCNH | P51946 | 1/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 3/20 | 0.54 |
| ▸ | METAP2 | P50579 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200380 | 0.81 | KDM1A (0.79) | MEN1KMT2AGAAACLYFFAR1 | |
| SCHEMBL7571635 | 0.81 | FFAR1 (0.66) | MEN1KMT2AGAAFFAR1CDK1 | |
| SCHEMBL7572541 | 0.78 | FFAR1 (0.62) | MEN1KMT2AGAAFFAR1CDK1 | |
| SCHEMBL7570517 | 0.77 | CYP2C9 (0.61) | MEN1KMT2AGAAFFAR1CDK1 | |
| SCHEMBL10583133 | 0.76 | HSD17B2 (0.58) | MEN1KMT2AGAAACLYFFAR1 | |
| SCHEMBL7577215 | 0.75 | POLB (0.57) | MEN1KMT2AGAAACLYFFAR1 | |
| SCHEMBL3985583 | 0.75 | METAP2 (0.72) | MEN1KMT2AGAAACLYKDM1A | |
| SCHEMBL6380677 | 0.75 | SLC20A2 (0.71) | MEN1KMT2AGAAACLYKDM1A | |
| SCHEMBL21999576 | 0.75 | ACLY (1.00) | MEN1KMT2AGAAACLYKDM1A | |
| SCHEMBL3988524 | 0.75 | ACLY (0.75) | MEN1KMT2AGAAACLYKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |