Halosulfuron

Halosulfuron

SCHEMBL7580413

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2c(C(=O)O)c(Cl)nn2C)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
GAA P10253 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.36
TTR P02766 1/20 0.36
PPOX P50336 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.36
FFAR1 O14842 2/20 0.34
KDR P35968 1/20 0.33
EGFR P00533 2/20 0.33
ERBB2 P04626 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PTGER4 P35408 1/20 0.31
SCN8A Q9UQD0 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.31
CCR2 P41597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Halosulfuron SCHEMBL7586640 0.91 MEN1 (0.31) LMNAGAAKDM4EMAPTHPGD
SCHEMBL7589011 0.90 MEN1 (0.37) LMNAGAAKDM4EMAPTHPGD
SCHEMBL7578313 0.87 NTRK1 (0.36) LMNAGAAKDM4EMAPTHPGD
Lactofen SCHEMBL7579973 0.86 MEN1 (0.44) LMNAGAAKDM4EMAPTHPGD
SCHEMBL7577529 0.85 GAA (0.33) LMNAGAAKDM4EMAPTHPGD
SCHEMBL7596990 0.85 LMNA (0.39) LMNAGAAKDM4EMAPTHPGD
Flupyrsulfuron SCHEMBL7580422 0.85 KMT2A (0.40) LMNAGAAKDM4EMAPTHPGD
Halosulfuron SCHEMBL7585865 0.85 TDP1 (0.56) LMNAGAAMAPTMEN1TTR
Flazasulfuron SCHEMBL7578001 0.83 LMNA (0.38) LMNAGAAKDM4EMAPTHPGD
Sulfosulfuron SCHEMBL7583513 0.82 NTRK1 (0.35) LMNAGAAKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT LMNA 3881/4885GAA 288/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.