Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181456 | 0.94 | RECQL (0.52) | CA12CA9TDP1POLBCASP6 | |
| SCHEMBL7834037 | 0.91 | ALDH1A1 (0.48) | CA12CA9TDP1POLBNPSR1 | |
| SCHEMBL9005826 | 0.84 | ALDH1A1 (0.54) | TDP1POLBNPSR1ALDH1A1ATM | |
| SCHEMBL1685394 | 0.84 | BRD4 (0.51) | TDP1NPSR1ALDH1A1GAATSHR | |
| SCHEMBL7737606 | 0.83 | CA12 (0.51) | CA12CA9TDP1POLBALDH1A1 | |
| SCHEMBL9835947 | 0.78 | LMNA (0.41) | ALDH1A1GAATSHRMAPTCYP3A4 | |
| SCHEMBL31391062 | 0.78 | CA12 (0.63) | CA12CA9TDP1POLBCASP6 | |
| SCHEMBL635553 | 0.78 | CA12 (0.63) | CA12CA9TDP1POLBCASP6 | |
| SCHEMBL10913560 | 0.77 | GAA (0.56) | POLBALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL10907099 | 0.76 | PTGES (0.56) | CA12CA9TDP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801663-B1 | CURABLE SEALER AND/OR ADHESIVE COMPOSITION, METHOD FOR COATING SAME AND COATED SUBSTRATES | MINNESOTA MINING & MFG (US) | 1999-08-18 | — | — | EP | claimed |
| EP-0459304-B1 | A one component sealant composition | ADCO PRODUCTS INC (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0450105-B1 | Room-temperature, moisture-curable, primerless, poluyrethane-based adhesive composition and method | ADCO PRODUCTS INC (US) | 1995-11-15 | — | — | EP | claimed |
| EP-0220409-B1 | GEM-DIHALO AND TETRAHALO-1,12-DIAMINO-4,9-DIAZA-DODECANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-11-27 | — | — | EP | claimed |