Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP16 | P51512 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576449 | 0.91 | ALDH1A1 (0.44) | ALDH1A1HTTPKMPOLBPTGS2 | |
| SCHEMBL7574610 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HTTPKMPOLBPTGS2 | |
| SCHEMBL2896066 | 0.86 | PTGS2 (0.41) | ALDH1A1HTTPTGS2MMP13 | |
| SCHEMBL4452953 | 0.86 | PSIP1 (0.43) | HTTHSD11B1LMNANPSR1 | |
| SCHEMBL2896059 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HTTPKMPOLBPGR | |
| SCHEMBL2634849 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HTTPKMPOLBCA4 | |
| Trifluoromethanesulfonic Acid SCHEMBL361656 | 0.84 | KCNH2 (0.46) | ALDH1A1HTTPKMCA4LTA4H | |
| SCHEMBL126675 | 0.84 | CA4 (0.59) | ALDH1A1HTTPTGS2CA4LTA4H | |
| SCHEMBL5707382 | 0.83 | ALDH1A1 (0.36) | ALDH1A1HTTPOLBMMP13MMP2 | |
| Anisole SCHEMBL28347603 | 0.82 | CA4 (0.58) | ALDH1A1HTTPKMPOLBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020196896-A1 | Exposure method, exposure apparatus, X-ray mask, semiconductor device and microstructure | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1193553-A2 | Exposure method, exposure apparatus, x-ray mask, semiconductor device and microstructure | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2002-04-03 | — | — | EP | disclosed |