Methabenzthiazuron

Methabenzthiazuron

SCHEMBL7583577

CCc1ccc(COc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc2)c(OC(C)C(=O)OC)c1.CNC(=O)N(C)c1nc2ccccc2s1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
PPARG P37231 3/20 0.32
PPARD Q03181 3/20 0.32
PPARA Q07869 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
TP53 P04637 1/20 0.31
THRB P10828 1/20 0.31
CACNA1H O95180 1/20 0.31
CACNA1B Q00975 1/20 0.31
ADAM17 P78536 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tebuthiuron SCHEMBL7580956 0.87 CYP3A4 (0.36)
SCHEMBL21300527 0.85 POLB (0.37) ALDH1A1PPARGADAM17SMN1; SMN2
SCHEMBL39056 0.85 POLB (0.37) ALDH1A1PPARGADAM17SMN1; SMN2
SCHEMBL5467634 0.79 L3MBTL1 (0.39) NPC1ALDH1A1RAB9APPARGMAPT
Clopyralid SCHEMBL7580470 0.79 PPARG (0.35) PPARGPPARDPPARAMEN1MAPT
Napropamide SCHEMBL7586388 0.79 ADAM17 (0.31) ADAM17SMN1; SMN2
SCHEMBL4829878 0.78 PPARG (0.40) PPARGPPARDPPARA
SCHEMBL4829867 0.78 PPARG (0.40) PPARGPPARDPPARA
SCHEMBL7587631 0.78 PPARG (0.32) PPARG
Prosulfocarb SCHEMBL7586375 0.78 LMNA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT NPC1 4238/4885ALDH1A1 812/4885RAB9A 1914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.