SCHEMBL7584451

SCHEMBL7584451

COCCOc1ccccc1S(=O)(=O)NC(=O)Nc1nc(OC)nc(OC)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.38
HTT P42858 1/20 0.36
KDM4E B2RXH2 3/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
FFAR1 O14842 1/20 0.35
THRB P10828 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MEN1 O00255 1/20 0.34
TTR P02766 1/20 0.34
PPOX P50336 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Logran SCHEMBL7576657 0.92 KDM4E (0.34) PPARGKDM4ELMNAHPGDGAA
Chlorsulfuron SCHEMBL7578067 0.88 KDM4E (0.38) KDM4ELMNAHPGDGAAMAPT
SCHEMBL7582061 0.87 MEN1 (0.37) KDM4ELMNAHPGDGAAMAPT
Lactofen SCHEMBL7582318 0.86 MEN1 (0.41) PPARGKDM4ELMNAMAPTNPC1
Prosulfuron SCHEMBL7575335 0.85 LMNA (0.34) PPARGKDM4ELMNAHPGDGAA
Acifluorfen SCHEMBL7585625 0.85 TDP1 (0.54) PPARGHTTKDM4ELMNAHPGD
Logran SCHEMBL7587995 0.84 KDM4E (0.31) KDM4EMAPTMEN1KMT2A
SCHEMBL7581301 0.83 ALDH1A1 (0.42) PPARGKDM4EMAPTFFAR1NPC1
Chlorimuron Ethyl SCHEMBL7582578 0.81 MRGPRX4 (0.36) PPARGKDM4ELMNAHPGDGAA
Iodosulfuron SCHEMBL7586575 0.81 LMNA (0.36) KDM4ELMNAHPGDGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPARG 777/4885HTT 1254/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.