Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL7103207 | 0.74 | CA5A (0.35) | — | |
| Hydrochloric Acid SCHEMBL27918591 | 0.72 | LMNA (0.51) | LMNANOS1MEN1NOS3KMT2A | |
| Hydrochloric Acid SCHEMBL7295060 | 0.71 | NOS1 (0.55) | LMNANOS1MEN1NOS3KMT2A | |
| SCHEMBL30525451 | 0.68 | — | — | |
| SCHEMBL6890012 | 0.66 | — | — | |
| SCHEMBL2519794 | 0.66 | LMNA (0.46) | LMNANOS1MEN1NOS3KMT2A | |
| Sulfuric Acid SCHEMBL11560480 | 0.65 | ALDH1A1 (0.33) | NOS1KDM4E | |
| Sulfuric Acid SCHEMBL11560479 | 0.65 | ALDH1A1 (0.33) | NOS1KDM4E | |
| SCHEMBL9843115 | 0.62 | POLB (0.42) | NOS3POLB | |
| SCHEMBL3164776 | 0.61 | ALDH1A1 (0.42) | LMNAKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204633-A1 | METHOD FOR PRODUCING 1-METHYL-3-NITROGUANIDINE | NIGU CHEMIE GMBH (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001014323-A1 | METHOD FOR PRODUCING 1-METHYL-3-NITROGUANIDINE | NIGU CHEMIE GMBH (DE) | 2001-03-01 | — | — | WO | disclosed |