Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509050 | 0.85 | MAPT (0.44) | MAPTKMT2ASMN1; SMN2HIF1ACYP1A2 | |
| SCHEMBL6529359 | 0.83 | MAPT (0.48) | MAPTKMT2AHIF1ACYP1A2CYP2C19 | |
| SCHEMBL2190401 | 0.82 | CES1 (0.56) | KMT2ASMN1; SMN2HIF1ACYP1A2CYP3A4 | |
| SCHEMBL11247 | 0.80 | KMT2A (0.46) | MAPTKMT2AHIF1ACYP1A2CYP3A4 | |
| SCHEMBL11778520 | 0.78 | CYP3A4 (0.42) | MAPTKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL28753479 | 0.74 | CES1 (0.44) | MAPTKMT2ASMN1; SMN2HIF1ACYP1A2 | |
| SCHEMBL2845811 | 0.74 | MAPT (0.55) | MAPTKMT2ASMN1; SMN2HIF1ACYP1A2 | |
| SCHEMBL22406298 | 0.73 | SMN1; SMN2 (0.44) | MAPTKMT2ASMN1; SMN2HIF1ACYP1A2 | |
| SCHEMBL8459554 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2HIF1ACYP1A2CYP3A4RECQL | |
| SCHEMBL29543860 | 0.73 | CTBP2 (0.47) | KMT2AHIF1ACYP1A2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10987351-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2021-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10987351-B2 | RORgamma modulators and uses thereof | RORB, RORC, RORA | MAPT 4111/4885KMT2A 2471/4885SMN1; SMN2 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.