Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.54 |
| ▸ | ACLY | P53396 | 4/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18299831 | 0.86 | SLC22A12 (0.51) | SLC22A12ACLYCCR2PTGES2PGR | |
| SCHEMBL21865747 | 0.86 | RXFP1 (0.55) | SLC22A12ACLYPTGES2PGRSTAT3 | |
| SCHEMBL7859592 | 0.86 | SLC22A12 (0.51) | SLC22A12ACLYCCR2PTGES2PGR | |
| SCHEMBL18299624 | 0.86 | SLC22A12 (0.51) | SLC22A12ACLYCCR2PTGES2PGR | |
| SCHEMBL7587888 | 0.84 | KEAP1 (0.54) | ACLY | |
| SCHEMBL21866537 | 0.82 | GAA (0.52) | SLC22A12ACLYCCR2PTGES2CYP19A1 | |
| SCHEMBL27519445 | 0.82 | MAPT (0.60) | SLC22A12ACLYCCR2PTGES2PGR | |
| SCHEMBL7496445 | 0.81 | ACLY (0.52) | ACLYCCR2PTGES2KAT6A | |
| SCHEMBL7940030 | 0.81 | HDAC1 (0.50) | SLC22A12ACLYCCR2PTGES2KAT6A | |
| SCHEMBL7490402 | 0.81 | GPR27 (0.51) | SLC22A12CCR2PTGES2ERBB2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |