Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22039428 | 1.00 | HTR7 (0.42) | HTR7RORCMEN1KMT2ATDP1 | |
| SCHEMBL27528621 | 0.87 | RORC (0.46) | RORCL3MBTL1DDB1CRBNPRKCZ | |
| SCHEMBL29779454 | 0.87 | RORC (0.46) | RORCL3MBTL1DDB1CRBNPRKCZ | |
| SCHEMBL29779329 | 0.87 | RORC (0.46) | RORCL3MBTL1DDB1CRBNPRKCZ | |
| SCHEMBL7589379 | 0.86 | L3MBTL1 (0.51) | RORCMEN1KMT2AL3MBTL1 | |
| SCHEMBL5620456 | 0.85 | LIPE (0.47) | L3MBTL1HCRTR2 | |
| SCHEMBL3496027 | 0.84 | GPR119 (0.47) | L3MBTL1 | |
| SCHEMBL7233985 | 0.84 | KDM1A (0.46) | MEN1KMT2AL3MBTL1DDB1CRBN | |
| SCHEMBL7193226 | 0.82 | GPR119 (0.50) | L3MBTL1HCRTR2 | |
| SCHEMBL7043305 | 0.82 | DRD2 (0.40) | RORCKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217802-B | Histone acetylase p300 inhibitor and application thereof | 海创药业股份有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-111217802-A | Histone acetylase p300 inhibitor and application thereof | 成都海创药业有限公司 | 2020-06-02 | — | — | CN | disclosed |
| US-6599924-B1 | 2-hetaryl-3,4 dihydro-2H-pyrrole pesticide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| CN-1323304-A | 2-hetaryl-3,4-dihydro-2h-pyrrole derivatives | BAYER AG (DE) | 2001-11-21 | — | — | CN | disclosed |
| EP-1121357-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021958-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-20 | — | — | WO | disclosed |