Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | CCR9 | P51686 | 5/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571564 | 0.83 | AR (0.60) | FFAR4PTGDR2MAPTSLC22A12 | |
| SCHEMBL7595506 | 0.81 | FFAR4 (0.57) | FFAR4CCR9FBP1 | |
| SCHEMBL4650259 | 0.81 | GPR119 (0.61) | FFAR4GPR119MAPTSLC22A12 | |
| SCHEMBL7591774 | 0.80 | TRPA1 (0.46) | FFAR4SLC40A1CCR9PTGDR2STAT3 | |
| SCHEMBL7577285 | 0.80 | FFAR4 (0.59) | FFAR4CCR9MAPT | |
| SCHEMBL7590053 | 0.78 | FFAR4 (0.59) | FFAR4SLC40A1CCR9MAPTFBP1 | |
| SCHEMBL7569763 | 0.78 | FFAR4 (0.59) | FFAR4SLC40A1CCR9MAPTFBP1 | |
| SCHEMBL7587888 | 0.78 | KEAP1 (0.54) | FFAR4MAPTACLY | |
| SCHEMBL7589336 | 0.78 | SLC22A12 (0.54) | SLC40A1STAT3SLC22A12ACLYCCR2 | |
| SCHEMBL7573010 | 0.77 | FFAR4 (0.52) | FFAR4CCR9STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |