Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378690 | 1.00 | CYP2A6 (0.41) | CYP2A6CYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL31462816 | 1.00 | CYP2A6 (0.41) | CYP2A6CYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL28433701 | 0.98 | CYP2A6 (0.40) | CYP2A6CYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL7590618 | 0.91 | MAPT (0.43) | CYP2A6CYP1A2MAPTHSD17B10TDP1 | |
| SCHEMBL5080119 | 0.89 | DHFR (0.40) | CYP2A6CYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL7568810 | 0.88 | HSD17B10 (0.40) | CYP2A6CYP1A2TSHRALDH1A1HSD17B10 | |
| SCHEMBL1042470 | 0.86 | CYP2A6 (0.42) | CYP2A6CYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL31566350 | 0.86 | CYP2A6 (0.42) | CYP2A6CYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL23943725 | 0.86 | CYP2A6 (0.38) | CYP2A6CYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL29424786 | 0.86 | MAPT (0.38) | CYP2A6CYP1A2MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710422-B1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-07 | — | — | EP | claimed |
| EP-3856738-B1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | QUIM SINTETICA S A (ES) | 2025-03-19 | — | — | EP | claimed |
| US-20240002400-A1 | ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES | AMGEN INC. (US) | 2024-01-04 | — | — | US | claimed |
| EP-4251604-A1 | ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES | Amgen Inc. (US) | 2023-10-04 | — | — | EP | claimed |
| US-11591314-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-02-28 | — | — | US | claimed |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | Química Sintética, S.A. (ES) | 2022-10-11 | — | — | US | claimed |
| WO-2022115400-A1 | ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES | AMGEN INC. (US) | 2022-06-02 | — | — | WO | claimed |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2022-02-03 | — | — | US | claimed |
| EP-2981560-B1 | CURING OF LIQUID THERMOSETTING RESINS | REICHHOLD LLC 2 (US) | 2021-10-13 | — | — | EP | claimed |
| US-11053188-B2 | Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-06 | — | — | US | claimed |
| US-20100311975-A1 | CATIONIC TRANSITION METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2010-12-09 | — | — | US | claimed |
| EP-2215101-A1 | CATIONIC TRANSITION METAL CATALYSTS | Kanata Chemical Technologies Inc. (CA) | 2010-08-11 | — | — | EP | claimed |
| WO-2009055912-A1 | CATIONIC TRANSITION METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2009-05-07 | — | — | WO | claimed |
| US-20080058522-A1 | Process For The Preparation Of Enantiomerically Enriched Beta Amino Acid Derivatives | MERCK SHARP & DOHME LLC | 2008-03-06 | — | — | US | claimed |
| EP-1411045-B1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2008-01-16 | — | — | EP | claimed |
| EP-1650207-B1 | Process for producing optically active 3-quinuclidinols | TAKASAGO PERFUMERY CO LTD (JP) | 2007-06-27 | — | — | EP | claimed |
| EP-1735269-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED BETA AMINO ACID DERIVATIVES | Merck & Co., Inc. (US) | 2006-12-27 | — | — | EP | claimed |
| US-6984738-B2 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU | 2006-01-10 | — | — | US | claimed |
| WO-2005097733-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED BETA AMINO ACID DERIVATIVES | MERCK & CO., INC. (US) | 2005-10-20 | — | — | WO | claimed |
| EP-1506965-A1 | PROPANOLAMINE DERIVATIVES, PROCESS FOR PREPARATION OF 3-N-METHYLAMINO-1-(2-THIENYL)-1-PROPANOLS AND PROCESS FOR PREPARATION OF PROPANOLAMINE DERIVATIVES | Mitsubishi Rayon Co., Ltd. (JP) | 2005-02-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591314-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | CYP2C8, CYP3A7, PARP8 | CYP2A6 120/4885CYP1A2 42/4885MAPT 2849/4885 |
| US-20080058522-A1 | Process For The Preparation Of Enantiomerically Enriched Beta Amino Acid Derivatives | ATIC, SLC1A5, SLC7A1 | CYP2A6 2926/4885CYP1A2 3306/4885MAPT 4363/4885 |
| US-20240002400-A1 | ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES | MCL1, BAK1, BCL2A1 | CYP2A6 2071/4885CYP1A2 860/4885MAPT 3468/4885 |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | S1PR1, S1PR4, S1PR3 | CYP2A6 2431/4885CYP1A2 2588/4885MAPT 3610/4885 |
| US-20100311975-A1 | CATIONIC TRANSITION METAL CATALYSTS | AP2M1, OPRM1, CD81 | CYP2A6 4473/4885CYP1A2 4560/4885MAPT 3803/4885 |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | S1PR1, S1PR4, S1PR3 | CYP2A6 2431/4885CYP1A2 2588/4885MAPT 3610/4885 |
| US-11053188-B2 | Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides | TBCB, ADORA2B, CCNB3 | CYP2A6 436/4885CYP1A2 126/4885MAPT 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.