Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601180 | 0.80 | FGFR1 (0.69) | CYP1A2TSHRFGFR1SLC22A6 | |
| SCHEMBL23228237 | 0.75 | CYP1A2 (0.72) | CYP1A2TSHRSMN1; SMN2CYP2D6MAPK1 | |
| SCHEMBL8466930 | 0.73 | CYP1A2 (0.72) | CYP1A2TSHRSMN1; SMN2CYP2D6MAPK1 | |
| SCHEMBL6426384 | 0.70 | CYP1A2 (0.59) | CYP1A2TSHRSMN1; SMN2CYP2D6ADORA2A | |
| SCHEMBL382916 | 0.70 | FGFR1 (0.66) | FGFR1SLC22A6NSD3SMN1; SMN2LMNA | |
| SCHEMBL8768263 | 0.70 | CYP1A2 (0.59) | CYP1A2TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9583305 | 0.68 | CYP1A2 (0.54) | CYP1A2TSHRSMN1; SMN2LMNAADORA2A | |
| SCHEMBL9561545 | 0.67 | ADORA2A (0.50) | CYP1A2FGFR1SLC22A6NSD3SMN1; SMN2 | |
| SCHEMBL4364344 | 0.67 | ADORA2A (0.70) | FGFR1SLC22A6NSD3SMN1; SMN2LMNA | |
| SCHEMBL2003349 | 0.67 | NSD3 (0.47) | CYP1A2TSHRFGFR1SLC22A6NSD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919562-B1 | PHOSPHONATE NUCLEOTIDE COMPOUNDS | MITSUBISHI CHEM CORP (JP) | 2002-11-06 | — | — | EP | disclosed |