Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 4/20 | 0.43 |
| ▸ | FPR2 | P25090 | 4/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569448 | 0.80 | DRD2 (0.45) | PRKDCFPR2PTPN2PTPN1PTPN6 | |
| Bromide SCHEMBL6178897 | 0.77 | MMP1 (0.40) | ROCK2PRKDCLIPEMMP1NAMPT | |
| SCHEMBL14525364 | 0.75 | SMN1; SMN2 (0.53) | FPR2FPR1DRD2 | |
| SCHEMBL23142748 | 0.74 | MAPKAPK2 (0.39) | PRKDCLIPEPTPN2PTPN1PTPN6 | |
| SCHEMBL13055402 | 0.73 | CYP17A1 (0.59) | LIPEPSMB8NAMPTDRD2CYP17A1 | |
| SCHEMBL23142816 | 0.73 | CYP17A1 (0.42) | PRKDCLIPEPSMB8NAMPTDRD2 | |
| SCHEMBL16493351 | 0.73 | FPR2 (0.56) | ROCK2LIPEFPR2MMP1FPR1 | |
| SCHEMBL30817405 | 0.73 | MAPT (0.50) | PRKDCLIPEPSMB8NAMPTDRD2 | |
| SCHEMBL3573442 | 0.72 | GPR119 (0.50) | PRKDCPTPN2PTPN1PTPN6NAMPT | |
| SCHEMBL29986622 | 0.72 | PRKDC (0.49) | PRKDCLIPEPSMB8NAMPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169186-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS GLYCINE ANTAGONISTS | DI FABIO ROMANO (IT) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169186-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS GLYCINE ANTAGONISTS | GLRA1, GRM1, GNMT | ROCK2 3403/4885PRKDC 4836/4885LIPE 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.