Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518963 | 0.84 | SMPD1 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7599649 | 0.83 | APP (0.41) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RAB9A | |
| SCHEMBL7602517 | 0.80 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RAB9A | |
| Metrafenone SCHEMBL30013482 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| Metrafenone SCHEMBL29408434 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| Metrafenone SCHEMBL20788 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL6740158 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RAB9A | |
| SCHEMBL6737783 | 0.77 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RAB9A | |
| SCHEMBL7524397 | 0.75 | TUBB4A (0.38) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL13409130 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155518-A1 | Method of detecting compounds that control fungal diseases via effects on sporulation | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |