Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602517 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7044465 | 0.85 | PDE4A (0.47) | APPSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7598060 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7602501 | 0.82 | THRA (0.46) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7518963 | 0.82 | SMPD1 (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL7601914 | 0.81 | MAPT (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7600520 | 0.80 | MAPT (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7603075 | 0.78 | MAPT (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6737783 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2APTPN1 | |
| Metrafenone SCHEMBL30013482 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155518-A1 | Method of detecting compounds that control fungal diseases via effects on sporulation | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |