SCHEMBL7598371

SCHEMBL7598371

C=Cc1ccccc1C(N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 1/20 0.39
GRM1 Q13255 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP2C19 P33261 2/20 0.37
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
ALPI P09923 1/20 0.36
PKM P14618 1/20 0.36
PTGS1 P23219 1/20 0.36
XIAP P98170 1/20 0.36
SLC7A5 Q01650 1/20 0.36
AKT1 P31749 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407902 1.00 MEN1 (0.39) MEN1KMT2ACYP1A2CYP3A4GRM1
SCHEMBL11376459 0.81 LMNA (0.48) KMT2ACYP2C19LMNAALDH1A1MAPK1
SCHEMBL24044801 0.80 MEN1 (0.48) MEN1KMT2ACYP1A2CYP3A4GRM1
SCHEMBL2928008 0.78 PTGS2 (0.43) CYP3A4CYP2C19LMNAALDH1A1MAPK1
SCHEMBL2802851 0.78 CYP1A2 (0.37) CYP1A2CYP2C19LMNAALDH1A1MAPK1
SCHEMBL27537238 0.76 SLC1A2 (0.37) MEN1KMT2ACYP1A2CYP2C19LMNA
SCHEMBL9960123 0.76 ALDH1A1 (0.44) MEN1KMT2ATDP1LMNAALDH1A1
SCHEMBL7993792 0.74 CYP2C19 (0.45) MEN1KMT2ACYP1A2CYP2C19LMNA
SCHEMBL27954218 0.74 SRC (0.38) CYP2C19LMNAALDH1A1MAPK1AKT1
SCHEMBL2944385 0.73 ALDH1A1 (0.46) MEN1KMT2ACYP3A4TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114126590-B Pharmaceutical preparation and method for producing the same 富士制药工业股份有限公司 2024-01-05 CN claimed
CN-114126590-A Pharmaceutical preparation and process for producing the same 富士制药工业股份有限公司 2022-03-01 CN claimed
EP-3960240-B1 PHARMACEUTICAL PREPARATION AND METHOD FOR PRODUCING SAME FUJI PHARMA CO LTD (JP) 2024-03-27 EP disclosed
CN-114126590-B Pharmaceutical preparation and method for producing the same 富士制药工业股份有限公司 2024-01-05 CN disclosed
US-20220211688-A1 PHARMACEUTICAL PREPARATION AND METHOD FOR PRODUCING THE SAME FUJI PHARMA CO., LTD. (JP) 2022-07-07 US disclosed
EP-3960240-A1 PHARMACEUTICAL PREPARATION AND METHOD FOR PRODUCING SAME Fuji Pharma Co., Ltd. (JP) 2022-03-02 EP disclosed
CN-114126590-A Pharmaceutical preparation and process for producing the same 富士制药工业股份有限公司 2022-03-01 CN disclosed
EP-0335560-B2 Controlled release pharmaceutical preparation and method for producing the same TANABE SEIYAKU CO (JP) 2002-01-23 EP disclosed
US-5254347-A Coating core with porous film of hydrophobic polymer TANABE SEIYAKU CO., LTD. (JP) 1993-10-19 US disclosed
EP-0335560-B1 CONTROLLED RELEASE PHARMACEUTICAL PREPARATION AND METHOD FOR PRODUCING THE SAME Tanabe Seiyaku Co., Ltd. (JP) 1993-07-28 EP disclosed
US-5068112-A Core containing active ingredient and succinic acid with surface porous film of cellulose TANABE SEIYAKU CO., LTD. (JP) 1991-11-26 US disclosed
EP-0335560-A2 Controlled release pharmaceutical preparation and method for producing the same Tanabe Seiyaku Co., Ltd. (JP) 1989-10-04 EP disclosed
US-4443497-A DISSOLVING, COATING, SOLVENTS, POLYMER, ETHYL CELLULOSE, ANTICOAGULANTS, DRUGS TANABE SEIYAKU CO., LTD. (JP) 1984-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211688-A1 PHARMACEUTICAL PREPARATION AND METHOD FOR PRODUCING THE SAME CDK9, CDK19, CHD9 MEN1 3115/4885KMT2A 900/4885CYP1A2 3031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.