⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755620 | 0.91 | — | — | |
| SCHEMBL3679699 | 0.84 | — | — | |
| SCHEMBL663826 | 0.83 | — | — | |
| SCHEMBL21050107 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL755514 | 0.72 | HCAR2 (0.31) | — | |
| SCHEMBL331865 | 0.72 | — | — | |
| SCHEMBL755621 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL35613 | 0.71 | ATM (0.40) | — | |
| SCHEMBL3674540 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL3673668 | 0.69 | PRKCA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207825-B8 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2207825-B1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2011-06-29 | — | — | EP | disclosed |
| EP-2207825-A1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | Johnson & Johnson Vision Care, Inc. (US) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009058207-A1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20090111905-A1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-04-30 | — | — | US | disclosed |