Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076 | 0.92 | KAT2B (0.69) | MAPTTDP1L3MBTL1ALDH1A1KAT2B | |
| SCHEMBL29377506 | 0.92 | KAT2B (0.69) | MAPTTDP1L3MBTL1ALDH1A1KAT2B | |
| SCHEMBL112296 | 0.92 | ALDH1A1 (0.68) | MAPTTDP1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL29580274 | 0.83 | KAT2B (0.74) | MAPTTDP1ALDH1A1KAT2BPOLB | |
| SCHEMBL4858189 | 0.83 | KAT2B (0.74) | MAPTTDP1ALDH1A1KAT2BPOLB | |
| SCHEMBL2796146 | 0.83 | MAPT (0.66) | MAPTTDP1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL29580293 | 0.83 | MAPT (0.66) | MAPTTDP1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL4863416 | 0.82 | KAT2B (0.72) | MAPTTDP1ALDH1A1KAT2BPOLB | |
| SCHEMBL1520169 | 0.80 | MAPT (0.64) | MAPTTDP1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL4640284 | 0.80 | KAT2B (0.64) | MAPTTDP1L3MBTL1ALDH1A1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020000012-A1 | Compositions and methods for dyeing keratin fibers, especially hair | WELLA AKTIENGESELLSCHAFT (DE) | 2002-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020000012-A1 | Compositions and methods for dyeing keratin fibers, especially hair | KRT18, DSG1, KRTCAP2 | MAPT 305/4885TDP1 3372/4885L3MBTL1 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.