Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 12/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602927 | 0.92 | MAPT (0.64) | ALDH1A1NPSR1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29580293 | 0.91 | MAPT (0.66) | ALDH1A1NPSR1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2796146 | 0.91 | MAPT (0.66) | ALDH1A1NPSR1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL1520169 | 0.88 | MAPT (0.64) | ALDH1A1NPSR1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL9034789 | 0.84 | ALDH1A1 (0.63) | ALDH1A1NPSR1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10935716 | 0.83 | ALDH1A1 (0.66) | ALDH1A1NPSR1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10804680 | 0.83 | ALDH1A1 (0.66) | ALDH1A1NPSR1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL127370 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 | |
| SCHEMBL8053888 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 | |
| SCHEMBL563763 | 0.83 | PKM (0.67) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 998 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263642-A2 | Colouring bleaches | Henkel AG & Co. KGaA (DE) | 2010-12-22 | — | — | EP | claimed |
| US-7799092-B2 | Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer | L'OREAL S.A. (FR) | 2010-09-21 | — | — | US | claimed |
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1787631-A1 | New dye precursor combinations | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-23 | — | — | EP | claimed |
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-20070033743-A1 | direct dyes | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| EP-1738800-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1738801-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-0646108-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| EP-0646109-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES. | OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| WO-1994000415-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-5037446-A | 2-nitroaniline derivatives and hair dyeing compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | claimed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-0226973-B1 | 4-BIS(2'-HYDROXYETHYL)AMINO-1-(3'-HYDROXYPROPYL)AMINO-2-NITRO-BENZENE, PROCESS FOR ITS PREPARATION AND MEANS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | claimed |
| US-4921504-A | 4-(N-ethyl-N-2-hydroxyethyl)-amino-1-(2 hydroxyethyl)-amino-2-nitrobenzene and compositions for dyeing hair containing the same | WELLA AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | claimed |
| EP-0184061-B1 | 4-(N-ETHYL,N-2'-HYDROXYETHYL)-AMINO-1-(2\"-HYDROXYETHYL)-AMINO-2-NITROBENZENE AND HAIR DYEING AGENTS | Wella Aktiengesellschaft (DE) | 1988-12-14 | — | — | EP | claimed |
| EP-0184061-A1 | 4-(N-ethyl,N-2'-hydroxyethyl)-amino-1-(2\"-hydroxyethyl)-amino-2-nitrobenzene and hair dyeing agents | Wella Aktiengesellschaft (DE) | 1986-06-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | KRT18, BRD7, KAT7 | ALDH1A1 930/4885NPSR1 3785/4885MAPT 730/4885 |
| US-20070033743-A1 | direct dyes | KRT18, DSG1, DSP | ALDH1A1 385/4885NPSR1 4002/4885MAPT 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.