SCHEMBL7605535

SCHEMBL7605535

CCOC(=O)CNC(=O)CNC(=O)c1cccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
HTT P42858 1/20 0.51
APOB P04114 7/20 0.48
MTTP P55157 10/20 0.47
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
RAB9A P51151 1/20 0.46
KDM4E B2RXH2 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7610756 0.96 APOB (0.51) L3MBTL1HTTAPOBMTTPPOLB
SCHEMBL7610500 0.89 APOB (0.51) L3MBTL1APOBMTTPPOLBPKM
SCHEMBL7615414 0.87 HTT (0.54) L3MBTL1HTTAPOBMTTPRXFP1
SCHEMBL7609278 0.83 ALDH1A1 (0.58) APOBMTTPPOLBRXFP1
SCHEMBL7605543 0.81 F3 (0.49) L3MBTL1APOBMTTP
SCHEMBL7605789 0.81 APOB (0.56) APOBMTTPRXFP1
SCHEMBL7607440 0.80 MTTP (0.57) HTTAPOBMTTP
SCHEMBL7612293 0.80 PPARG (0.52) L3MBTL1APOBMTTPKDM4ERXFP1
SCHEMBL7607281 0.80 LMNA (0.55) L3MBTL1HTTAPOBMTTPRXFP1
SCHEMBL7605815 0.80 APOB (0.63) L3MBTL1HTTAPOBMTTPRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments MTTP, CETP, FABP1 L3MBTL1 3333/4885HTT 3107/4885APOB 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.