Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.33 |
| ▸ | PIM1 | P11309 | 9/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 2/20 | 0.30 |
| ▸ | CLK3 | P49761 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.30 |
| ▸ | SGK1 | O00141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760625 | 1.00 | SSTR4 (0.33) | SSTR4PIM1PIM2GPR119PTPN11 | |
| SCHEMBL299903 | 1.00 | SSTR4 (0.33) | SSTR4PIM1PIM2GPR119PTPN11 | |
| SCHEMBL290047 | 0.80 | GPR119 (0.36) | GPR119 | |
| SCHEMBL300080 | 0.80 | GPR119 (0.36) | GPR119 | |
| SCHEMBL3512362 | 0.80 | GPR119 (0.36) | GPR119 | |
| SCHEMBL757014 | 0.80 | GPR119 (0.36) | GPR119 | |
| SCHEMBL756592 | 0.77 | GPR119 (0.44) | GPR119 | |
| SCHEMBL756593 | 0.77 | GPR119 (0.44) | GPR119 | |
| SCHEMBL288817 | 0.77 | GPR119 (0.41) | GPR119PTPN11KCNH2 | |
| SCHEMBL759311 | 0.77 | GPR119 (0.41) | GPR119PTPN11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052130-A1 | GPR 119 MODULATORS | PFIZER INC. | 2012-03-01 | — | — | US | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052130-A1 | GPR 119 MODULATORS | GPR119, GPR39, GPR65 | SSTR4 303/4885PIM1 4329/4885PIM2 3921/4885 |
| US-20100285145-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR39 | SSTR4 284/4885PIM1 4385/4885PIM2 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.