SCHEMBL760855

SCHEMBL760855

C[Si](C)(C)c1ccc(Nc2ccc3ccccc3c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.66
HSD17B10 Q99714 3/20 0.66
CYP3A4 P08684 2/20 0.66
HPGD P15428 1/20 0.66
CYP26A1 O43174 2/20 0.48
EPHX2 P34913 1/20 0.47
MAPT P10636 4/20 0.46
HIF1A Q16665 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.44
SIRT1 Q96EB6 1/20 0.44
SIRT3 Q9NTG7 1/20 0.44
SNCA P37840 1/20 0.44
DHODH Q02127 1/20 0.42
DHFR P00374 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18271560 0.85 ALDH1A1 (0.51) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL29352988 0.84 ALDH1A1 (0.91) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL9513153 0.84 ALDH1A1 (0.91) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL39488 0.84 ALDH1A1 (0.91) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
Charcoal, Activated SCHEMBL29831131 0.82 ALDH1A1 (0.86) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL29673631 0.82 ALDH1A1 (0.86) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL29386674 0.82 ALDH1A1 (0.86) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL182655 0.82 ALDH1A1 (0.86) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL3739909 0.82 ALDH1A1 (0.86) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1
SCHEMBL18271470 0.81 ALDH1A1 (0.71) ALDH1A1HSD17B10CYP3A4HPGDCYP26A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-06-25 US disclosed
US-11980088-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-07 US disclosed
CN-113964276-A Organic electroluminescent device and amine compound for organic electroluminescent device 三星显示有限公司 2022-01-21 CN disclosed
US-20220020930-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-01-20 US disclosed
US-20220020930-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-01-20 US disclosed
US-20180226585-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC APPARATUS THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-08-09 US disclosed
US-9831445-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed
US-9831445-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed
US-9831445-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed
US-20160172594-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-16 US disclosed
US-20160172594-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-16 US disclosed
US-20160172594-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-16 US disclosed
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed
US-8137823-B2 Anthracene derivatives, process for preparation thereof, and organic electronic light emitting device using the same LG CHEM, LTD. (KR) 2012-03-20 US disclosed
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160172594-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ALDH1A1 438/4885HSD17B10 1947/4885CYP3A4 774/4885
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof PIEZO1, VDAC2, ORAI2 ALDH1A1 1855/4885HSD17B10 3125/4885CYP3A4 1553/4885
US-20180226585-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC APPARATUS THEREOF PIEZO1, ORAI2, VDAC2 ALDH1A1 1529/4885HSD17B10 3019/4885CYP3A4 1563/4885
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same XPOT, ALAD, APRT ALDH1A1 434/4885HSD17B10 1129/4885CYP3A4 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.