SCHEMBL7608593

SCHEMBL7608593

O=c1[nH]c(=O)n(Cc2ccc(O)cc2)c(=O)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 8/20 0.45
KMT2A Q03164 5/20 0.45
MAPT P10636 4/20 0.45
MEN1 O00255 3/20 0.45
MTOR P42345 3/20 0.45
KDM4E B2RXH2 4/20 0.43
DAO P14920 1/20 0.42
HPGD P15428 5/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP3A4 P08684 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PGR P06401 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
DBH P09172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2337883 0.82 HPGD (0.58) LMNAHTTALDH1A1KMT2AMAPT
SCHEMBL11721250 0.81 P2RX4 (0.49) LMNAALDH1A1KMT2AMAPTMEN1
SCHEMBL2305294 0.79 ESR1 (0.48) ALDH1A1HPGDCYP3A4CYP1A2POLB
SCHEMBL7603399 0.76 ESR1 (0.49) LMNAHTTALDH1A1KMT2AMAPT
SCHEMBL7601523 0.73 THRB (0.42) LMNAHTTALDH1A1KMT2AMAPT
SCHEMBL7631700 0.73 MAOA (0.40) HTTALDH1A1KMT2AMAPTMEN1
SCHEMBL14725062 0.72 BRAF (0.48) LMNAHTTALDH1A1KMT2AMAPT
SCHEMBL10790349 0.69 ESR2 (0.51) HTTALDH1A1KMT2AMAPTMEN1
SCHEMBL456005 0.69 ALDH1A1 (0.49) LMNAHTTALDH1A1KMT2AMAPT
Phenol SCHEMBL28919230 0.67 MEN1 (0.47) LMNAALDH1A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4412062-A CURE RETARDERS; TETRAOXAPHOSPHASDIROUNDECANES, 4-HYDROXYBENZYL ISOCYANURATES, N-HYDROCARBYLTHIOPHTHALIMIDES AND TRIHYDROCARBYL TRITHIOPHOSPHITES PHILLIPS PETROLEUM COMPANY (US) 1983-10-25 US claimed
JP-63207837-A None JP disclosed
JP-63039940-A None JP disclosed
US-6451888-B1 Solid stabilizer composition with improved hydrolytic stability GENERAL ELECTRIC COMPANY 2002-09-17 US disclosed
US-6033600-A PENTAERYTHRITOL PHOSPHITE, A HINDERED PHENOLIC ISOCYANURATE, A METAL SALT OF A FATTY ACID AND HYDROTALCITE. GENERAL ELECTRIC COMPANY (US) 2000-03-07 US disclosed
EP-0685516-B1 Solid stabilizer composition with improved hydrolytic stability GEN ELECTRIC (US) 1999-08-04 EP disclosed
EP-0685516-A1 Solid stabilizer composition with improved hydrolytic stability GENERAL ELECTRIC COMPANY (US) 1995-12-06 EP disclosed
US-5162406-A Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol THE DOW CHEMICAL COMPANY (US) 1992-11-10 US disclosed
EP-0246190-B1 DERIVATIVES OF ISOCYANURIC ACID CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
CN-88100675-A ANTIOXIDANT AROMATIC FLUOROPHOSPHITES 1988-11-09 CN disclosed
EP-0110293-A2 Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof The B.F. GOODRICH Company (US) 1984-06-13 EP disclosed
EP-0106169-A1 Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof The B.F. GOODRICH Company (US) 1984-04-25 EP disclosed
US-4444929-A Unsymmetrical phosphite-phenolic isocyanurate stabilizer combinations THE B. F. GOODRICH COMPANY (US) 1984-04-24 US disclosed
EP-0104643-A2 5-Membered cyclic phosphonates and compositions thereof The B.F. GOODRICH Company (US) 1984-04-04 EP disclosed
US-4439564-A 5-Membered cyclic phosphonates and compositions thereof THE B. F. GOODRICH CO. (US) 1984-03-27 US disclosed
US-4415686-A Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof THE B. F. GOODRICH COMPANY (US) 1983-11-15 US disclosed
US-4412062-A CURE RETARDERS; TETRAOXAPHOSPHASDIROUNDECANES, 4-HYDROXYBENZYL ISOCYANURATES, N-HYDROCARBYLTHIOPHTHALIMIDES AND TRIHYDROCARBYL TRITHIOPHOSPHITES PHILLIPS PETROLEUM COMPANY (US) 1983-10-25 US disclosed
US-4412062-A CURE RETARDERS; TETRAOXAPHOSPHASDIROUNDECANES, 4-HYDROXYBENZYL ISOCYANURATES, N-HYDROCARBYLTHIOPHTHALIMIDES AND TRIHYDROCARBYL TRITHIOPHOSPHITES PHILLIPS PETROLEUM COMPANY (US) 1983-10-25 US disclosed
US-4025486-A PENTAERYTHRITOL PHOSPHITE COMBINATIONS AS ULTRAVIOLET LIGHT STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1977-05-24 US disclosed
JP-S06339940-A 0001-01-01 JP disclosed