SCHEMBL7609501

SCHEMBL7609501

O=C1C=CC(=O)N1c1ccccc1OC(F)F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.61
TLR9 Q9NR96 3/20 0.55
ALDH1A1 P00352 2/20 0.50
HSP90AA1 P07900 2/20 0.50
PKM P14618 2/20 0.50
CCR6 P51684 2/20 0.50
ATM Q13315 2/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
FAAH O00519 1/20 0.47
TNF P01375 1/20 0.42
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
G6PD P11413 1/20 0.40
KCNN4 O15554 2/20 0.39
DRD1 P21728 1/20 0.38
APLNR P35414 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10834529 0.82 MGLL (0.66) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL11050403 0.79 NR1H2 (0.44) MGLLALDH1A1MEN1KMT2ATNF
SCHEMBL9320871 0.79 MGLL (0.71) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL10398325 0.77 MGLL (0.69) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL29439366 0.76 MGLL (1.00) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL141734 0.76 MGLL (1.00) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL29754607 0.74 MGLL (0.65) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL29065798 0.74 MGLL (0.65) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL121404 0.73 TLR9 (1.00) MGLLTLR9ALDH1A1HSP90AA1PKM
SCHEMBL29377102 0.73 TLR9 (1.00) MGLLTLR9ALDH1A1HSP90AA1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0726252-B1 Process for the preparation of N-substituted cyclic imides BAYER AG (DE) 2002-04-17 EP disclosed
US-5773630-A REACTION OF ANHYDRIDE WITH PRIMARY AMINE TO FORM CYCLIC IMIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
EP-0726252-A1 Process for the preparation of N-substituted cyclic imides BAYER AG (DE) 1996-08-14 EP disclosed