Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HK1 | P19367 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15805858 | 0.86 | PDPK1 (0.72) | PDPK1CYP2A6LOXL2RAB9APTGDR2 | |
| SCHEMBL16159287 | 0.82 | PDPK1 (0.67) | PDPK1CYP2A6LOXL2RAB9APTGDR2 | |
| SCHEMBL4425765 | 0.79 | PDPK1 (0.74) | PDPK1CYP2A6LOXL2RAB9APTGDR2 | |
| SCHEMBL468088 | 0.78 | PDPK1 (0.60) | PDPK1CYP2A6LOXL2RAB9AALDH1A1 | |
| SCHEMBL173979 | 0.78 | PDPK1 (0.60) | PDPK1CYP2A6LOXL2ALDH1A1MAPT | |
| SCHEMBL31609722 | 0.78 | PDPK1 (0.60) | PDPK1CYP2A6LOXL2RAB9ACYP19A1 | |
| SCHEMBL13025 | 0.78 | PDPK1 (0.60) | PDPK1CYP2A6LOXL2ALDH1A1HPGD | |
| SCHEMBL11153399 | 0.78 | PDPK1 (0.60) | PDPK1CYP2A6LOXL2RAB9APTGDR2 | |
| SCHEMBL20550702 | 0.78 | PDPK1 (0.60) | PDPK1CYP2A6LOXL2CYP19A1PTGDR2 | |
| SCHEMBL30668080 | 0.78 | PDPK1 (0.60) | PDPK1CYP2A6LOXL2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103471-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | ASSEMBLY BIOSCIENCES INC (US) | 2026-04-16 | — | — | US | disclosed |
| US-20250376478-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | ASSEMBLY BIOSCIENCES INC (US) | 2025-12-11 | — | — | US | disclosed |
| EP-4581029-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | Assembly Biosciences, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2024049760-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| US-20230322691-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CANON KABUSHIKI KAISHA (JP) | 2023-10-12 | — | — | US | disclosed |
| US-20230322691-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CANON KABUSHIKI KAISHA (JP) | 2023-10-12 | — | — | US | disclosed |
| US-10710978-B2 | STK4 inhibitors for treatment of hematologic malignancies | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20180111916-A1 | STK4 INHIBITORS FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES | FONDAZIONE CENTRO SAN RAFFAELE (IT) | 2018-04-26 | — | — | US | disclosed |
| WO-2016161145-A1 | STK4 INHIBITORS FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20140315886-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-10-23 | — | — | US | disclosed |
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | CELLCEUTIX CORPORATION (US) | 2014-10-16 | — | — | US | disclosed |
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | CELLCEUTIX CORPORATION (US) | 2014-10-16 | — | — | US | disclosed |
| WO-2014093225-A2 | POLYCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CELLCEUTIX CORPORATION (US) | 2014-06-19 | — | — | WO | disclosed |
| CN-103313970-A | Novel bicyclic compound or salt thereof | TAIHO PHARMACEUTICAL CO LTD | 2013-09-18 | — | — | CN | disclosed |
| CN-101189233-A | Substituted diazabicycloalkane derivatives as ligands for the alpha 7 nicotinic acetylcholine receptor | ABBOTT LAB (US) | 2008-05-28 | — | — | CN | disclosed |
| US-6423471-B1 | TITANOCENE, ETHYLENICALLY UNSATURATED MONOMER, AND PIGMENT; PHOTOPOLYMERIZABLE | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-0385496-A2 | Color light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| EP-0297804-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1989-01-04 | — | — | EP | disclosed |
| EP-0105425-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103471-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | TK1, UNG, SMCHD1 | PDPK1 2756/4885CYP2A6 4355/4885LOXL2 3289/4885 |
| US-20230322691-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CCNT1, CCNE2, SCO2 | PDPK1 3978/4885CYP2A6 658/4885LOXL2 65/4885 |
| US-20180111916-A1 | STK4 INHIBITORS FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES | STK4, STK3, STK11 | PDPK1 56/4885CYP2A6 4266/4885LOXL2 2678/4885 |
| US-10710978-B2 | STK4 inhibitors for treatment of hematologic malignancies | STK4, STK3, STK11 | PDPK1 56/4885CYP2A6 4266/4885LOXL2 2678/4885 |
| US-20250376478-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | TYMP, TK1, TREH | PDPK1 362/4885CYP2A6 4378/4885LOXL2 4442/4885 |
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | ALG1, CD44, MUC1 | PDPK1 2134/4885CYP2A6 3440/4885LOXL2 1063/4885 |
| US-20140315886-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP2CA, PPP4C, PPP3CB | PDPK1 495/4885CYP2A6 3927/4885LOXL2 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.