Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606265 | 0.82 | SMPD1 (0.58) | PARP10PARP15KMT2ASMPD1ATM | |
| SCHEMBL29602721 | 0.78 | LMNA (0.61) | KMT2AMEN1ATMKDM4ECYP1A2 | |
| SCHEMBL1033641 | 0.78 | LMNA (0.61) | KMT2AMEN1ATMKDM4ECYP1A2 | |
| SCHEMBL23094269 | 0.77 | ALDH1A1 (0.76) | KMT2AMEN1L3MBTL1POLBKDM4E | |
| SCHEMBL6836482 | 0.77 | KMT2A (0.59) | PARP10PARP15KMT2AMEN1L3MBTL1 | |
| SCHEMBL12149587 | 0.76 | FDPS (0.70) | PARP10PARP15KMT2AMEN1L3MBTL1 | |
| SCHEMBL2697142 | 0.76 | ALDH1A1 (0.69) | PARP10PARP15KMT2AMEN1TRPM5 | |
| SCHEMBL13819281 | 0.76 | PARP15 (0.48) | PARP10PARP15KMT2AMEN1SMPD1 | |
| SCHEMBL4163008 | 0.76 | MAPK1 (0.63) | KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL17130187 | 0.75 | L3MBTL1 (0.52) | PARP10PARP15KMT2AMEN1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968179-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| US-6277849-B1 | FOR PROTECTION OF PLANTS AGAINST PHYTOPATHOGENIC MICROORGANISM INFESTATION | SYNGENTA CROP PROTECTION, INC. | 2001-08-21 | — | — | US | disclosed |
| EP-0968179-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | Novartis AG (CH) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998038161-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | NOVARTIS AG (CH) | 1998-09-03 | — | — | WO | disclosed |