Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094189 | 0.86 | KDM4E (1.00) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL21467982 | 0.84 | L3MBTL1 (0.79) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL23094227 | 0.82 | CYP3A4 (1.00) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL23094204 | 0.77 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL23094192 | 0.77 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7610095 | 0.77 | PARP10 (0.57) | L3MBTL1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL23094232 | 0.76 | L3MBTL1 (1.00) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL23094230 | 0.76 | L3MBTL1 (0.76) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL23094206 | 0.76 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL23094200 | 0.75 | LMNA (0.74) | ALDH1A1L3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947188-B2 | Small molecule ferroptosis inducers | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947188-B2 | Small molecule ferroptosis inducers | GPX4, AIFM2, GPX1 | ALDH1A1 845/4885L3MBTL1 2077/4885MAPT 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.