SCHEMBL7612467

SCHEMBL7612467

CC(c1c[nH]c2ccccc12)C(N)C(=O)NCCc1c[nH]c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.64
KMT2A Q03164 6/20 0.64
TSHR P16473 2/20 0.64
ALDH1A1 P00352 2/20 0.64
MAPT P10636 2/20 0.64
KDM4E B2RXH2 1/20 0.64
CYP3A4 P08684 1/20 0.64
ALOX15 P16050 1/20 0.64
MAPK1 P28482 1/20 0.64
HSD17B10 Q99714 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
CTSC P53634 1/20 0.63
LMNA P02545 1/20 0.62
CYP1A2 P05177 1/20 0.62
PKM P14618 1/20 0.62
CYP2C19 P33261 1/20 0.62
BLM P54132 1/20 0.62
TACR3 P29371 1/20 0.57
NLN Q9BYT8 1/20 0.57
MMP9 P14780 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7677879 0.87 MEN1 (0.67) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL10554058 0.86 MEN1 (0.64) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL761706 0.85 MEN1 (0.75) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL15145390 0.82 CTSC (0.71) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL17037428 0.82 MEN1 (0.70) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL18595162 0.81 MEN1 (0.76) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL7615745 0.81 HDAC8 (0.74) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL15398876 0.81 CTSC (0.71) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL2824958 0.80 AANAT (0.67) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL9118606 0.80 MEN1 (0.71) MEN1KMT2ATSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020091090-A1 Somatostatin antagonists and agonists COLE BRIDGET M (US) 2002-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091090-A1 Somatostatin antagonists and agonists GHSR, GHRHR, SSTR3 MEN1 882/4885KMT2A 1634/4885TSHR 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.