SCHEMBL7612909

SCHEMBL7612909

CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CNC(=O)O)CC(C)C

nearest known ligand 0.71

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 16/20 0.71
MMP2 P08253 8/20 0.71
MMP9 P14780 6/20 0.71
MMP3 P08254 5/20 0.71
MMP8 P22894 4/20 0.71
MMP7 P09237 3/20 0.71
FCER2 P06734 3/20 0.71
MMP12 P39900 1/20 0.57
MMP13 P45452 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7616099 0.89 MMP1 (0.73) MMP1MMP2MMP9MMP3MMP8
SCHEMBL6434826 0.88 MMP2 (0.73) MMP1MMP2MMP9MMP3MMP8
SCHEMBL4670160 0.87 MMP1 (0.78) MMP1MMP2MMP9MMP3MMP8
SCHEMBL5099222 0.86 MMP2 (0.80) MMP1MMP2MMP9MMP3MMP8
SCHEMBL5502507 0.83 MMP2 (1.00) MMP1MMP2MMP9MMP3MMP8
SCHEMBL10633276 0.81 MMP1 (0.65) MMP1MMP2MMP9MMP3MMP8
SCHEMBL7330972 0.81 MMP1 (0.66) MMP1MMP2MMP9MMP3MMP8
SCHEMBL7330965 0.81 MMP1 (0.66) MMP1MMP2MMP9MMP3MMP8
SCHEMBL28221967 0.81 MMP1 (0.66) MMP1MMP2MMP9MMP3MMP8
SCHEMBL6577614 0.81 MMP2 (0.80) MMP1MMP2MMP9MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020082200-A1 Use of inhibitors of human S-CD23 SMITHKLINE BEECHAM P.1.C. 2002-06-27 US claimed
US-20020082200-A1 Use of inhibitors of human S-CD23 SMITHKLINE BEECHAM P.1.C. 2002-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082200-A1 Use of inhibitors of human S-CD23 TIMP3, MMP3, MMP13 MMP1 7/4885MMP2 10/4885MMP9 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.