Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614729 | 1.00 | HTR6 (0.43) | HTR6SFRP1BAZ2BMAPTCFTR | |
| SCHEMBL7614732 | 1.00 | HTR6 (0.43) | HTR6SFRP1BAZ2BMAPTCFTR | |
| SCHEMBL6196157 | 0.85 | HTR6 (0.53) | HTR6SFRP1BAZ2BMAPTCFTR | |
| SCHEMBL6201924 | 0.81 | SFRP1 (0.49) | SFRP1GPR119PIK3CA | |
| SCHEMBL6201926 | 0.81 | SFRP1 (0.49) | SFRP1GPR119PIK3CA | |
| SCHEMBL6200793 | 0.74 | HTR6 (0.50) | HTR6SFRP1 | |
| SCHEMBL6200791 | 0.74 | HTR6 (0.50) | HTR6SFRP1 | |
| SCHEMBL6200798 | 0.74 | HTR6 (0.50) | HTR6SFRP1 | |
| SCHEMBL6200573 | 0.72 | HTR6 (0.57) | HTR6BAZ2BMAPT | |
| SCHEMBL6038224 | 0.70 | HTR6 (0.54) | HTR6BAZ2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020160999-A1 | Substituted indolines | PHARMACIA & UPJOHN COMPANY | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160999-A1 | Substituted indolines | TPH1, TPH2, NLN | HTR6 16/4885SFRP1 4249/4885BAZ2B 3542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.