Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | MMP9 | P14780 | 1/20 | 0.65 |
| ▸ | AANAT | Q16613 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.64 |
| ▸ | CDK4 | P11802 | 1/20 | 0.63 |
| ▸ | CCND1 | P24385 | 1/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399398 | 1.00 | MEN1 (0.72) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL1972441 | 0.86 | USP2 (0.77) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL29991148 | 0.86 | USP2 (0.77) | MEN1KMT2ALMNACYP1A2PKM | |
| Nb-Acetyltryptamine SCHEMBL468850 | 0.84 | MEN1 (1.00) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL3629173 | 0.84 | AANAT (0.70) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL8829876 | 0.83 | CCKBR (0.68) | MEN1KMT2ALMNACYP1A2PKM | |
| Nb-Acetyltryptamine SCHEMBL29669230 | 0.83 | MEN1 (0.97) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL5745010 | 0.83 | MEN1 (0.67) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL6394942 | 0.82 | MEN1 (0.76) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL761706 | 0.82 | MEN1 (0.75) | MEN1KMT2ALMNACYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | MEN1 3832/4885KMT2A 37/4885LMNA 2203/4885 |
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | MEN1 234/4885KMT2A 3668/4885LMNA 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.