Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | CALCR | P30988 | 9/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.43 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299911 | 0.78 | AGTR1 (0.47) | MAPK8MAPK9MAPK10CALCRCALCRL | |
| SCHEMBL31257034 | 0.77 | CALCRL (0.50) | CALCRL | |
| SCHEMBL38664551 | 0.76 | CALCR (0.51) | CALCRC5AR1 | |
| SCHEMBL29607579 | 0.75 | SLC6A2 (0.49) | CALCRAPLNRF2CALCRL | |
| SCHEMBL9396858 | 0.75 | MAPK8 (0.53) | MAPK8MAPK9MAPK10CALCRAPLNR | |
| SCHEMBL29608084 | 0.75 | APLNR (0.50) | CALCRAPLNRC5AR1RAMP3F2 | |
| SCHEMBL32677404 | 0.75 | XIAP (0.49) | F2CALCRL | |
| SCHEMBL32677407 | 0.75 | XIAP (0.49) | F2CALCRL | |
| SCHEMBL30913236 | 0.74 | REN (0.51) | CALCRF2 | |
| SCHEMBL29608394 | 0.74 | REN (0.49) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020119917-A1 | ANTI-INFLAMMATORY PEPTIDES DERIVED FROM C-REACTIVE PROTEIN | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2002-08-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119917-A1 | ANTI-INFLAMMATORY PEPTIDES DERIVED FROM C-REACTIVE PROTEIN | CTSE, CTSG, CTSL | MAPK8 2249/4885MAPK9 1909/4885MAPK10 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.