Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162887 | 0.82 | SOAT2 (0.46) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL287564 | 0.78 | SOAT2 (0.51) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL7206928 | 0.73 | FABP3 (0.41) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL7207657 | 0.67 | FABP3 (0.44) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL2779847 | 0.66 | SOAT2 (0.62) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL7109323 | 0.66 | FABP3 (0.39) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL8137246 | 0.66 | FABP3 (0.57) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL8136292 | 0.64 | FABP4 (0.50) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL7206924 | 0.63 | SOAT2 (0.39) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL7207662 | 0.63 | FABP4 (0.58) | FABP3FABP4FABP5SOAT2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263421-A2 | THE DUAL INHIBITOR OF CHOLESTERYL ESTER AND WAX ESTER SYNTHESIS AVASIMIBE FOR TREATING SEBACEOUS GLAND DISORDERS | Warner-Lambert Company LLC (US) | 2002-12-11 | — | — | EP | claimed |
| WO-2001056556-A2 | DUAL INHIBITORS OF CHOLESTERYL ESTER AND WAX ESTER SYNTHESIS FOR SEBACEOUS GLAND DISORDERS | WARNER-LAMBERT COMPANY (US) | 2001-08-09 | — | — | WO | claimed |