SCHEMBL762288

SCHEMBL762288

CCN1c2ccccc2Oc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 10/20 0.49
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
P2RX1 P51575 2/20 0.46
SIGMAR1 Q99720 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
PIM1 P11309 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MAPK1 P28482 2/20 0.43
TNNI3 P19429 1/20 0.43
TNNT2 P45379 1/20 0.43
TNNC1 P63316 1/20 0.43
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
SMPD1 P17405 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30764130 1.00 P2RX4 (0.49) P2RX4SLC1A3SLC1A2SLC1A1P2RX1
SCHEMBL15607139 0.84 AHR (0.50) P2RX4SLC1A3SLC1A2SLC1A1P2RX1
SCHEMBL10336956 0.84 SLC1A3 (0.39) P2RX4SLC1A3SLC1A2SLC1A1P2RX1
SCHEMBL10040710 0.84 SLC1A3 (0.42) P2RX4SLC1A3SLC1A2SLC1A1P2RX1
SCHEMBL10069652 0.84 P2RX4 (0.40) P2RX4SLC1A3SLC1A2SLC1A1P2RX1
SCHEMBL29061601 0.83 SLC1A3 (0.41) P2RX4SLC1A3SLC1A2SLC1A1P2RX1
SCHEMBL29759083 0.83 SIGMAR1 (0.50) P2RX4P2RX1SIGMAR1HDAC3HDAC6
SCHEMBL7696530 0.83 SIGMAR1 (0.50) P2RX4P2RX1SIGMAR1HDAC3HDAC6
SCHEMBL23544470 0.82 SLC1A3 (0.40) P2RX4SLC1A3SLC1A2SLC1A1P2RX1
SCHEMBL8401275 0.82 HDAC3 (0.53) P2RX4HDAC3HDAC6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190324339-A1 HYBRID ELECTROCHROMIC DEVICES AND METHODS HIVISQ TECHNOLOGIES, SOCIEDAD LIMITADA (ES) 2019-10-24 US claimed
EP-0707637-B1 ENHANCEMENT OF LACCASE REACTIONS NOVOZYMES AS (DK) 2005-11-02 EP claimed
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method L'OREAL S.A. (FR) 2004-03-18 US claimed
US-20040025265-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method LANG GERARD (FR) 2004-02-12 US claimed
CN-1443058-A Enzyme composition for bleaching human keratinous fibres and bleaching method OREAL (FR) 2003-09-17 CN claimed
US-20030159706-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method L'OREAL S.A. (FR) 2003-08-28 US claimed
EP-1304998-A1 ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD L'OREAL (FR) 2003-05-02 EP claimed
EP-1304997-A1 ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD L'OREAL (FR) 2003-05-02 EP claimed
EP-1304996-A1 ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD L'OREAL (FR) 2003-05-02 EP claimed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US claimed
EP-0912097-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1999-05-06 EP claimed
US-5885304-A AROMATIC COMPOUNDS CONTAINING AT LEAST TWO RINGS, AT LEAST ONE SUBSTITUTED WITH NITROGEN OXYGEN, OR SULFUR NOVO NORDISK A/S (DK) 1999-03-23 US claimed
WO-1998046820-A1 ENZYMATIC DISCHARGE PRINTING OF DYED TEXTILES NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1998-10-22 WO claimed
US-5795855-A DETERGENTS NOVO NORDISK A/S 1998-08-18 US claimed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 WO claimed
EP-0707637-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1996-04-24 EP claimed
EP-0679183-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK A/S (DK) 1995-11-02 EP claimed
WO-1995001426-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1995-01-12 WO claimed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 WO claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159706-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, LPO, MPO P2RX4 3376/4885SLC1A3 4751/4885SLC1A2 4820/4885
US-20040025265-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, LPO, ALDH1A2 P2RX4 4155/4885SLC1A3 4585/4885SLC1A2 4685/4885
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, COXFA4, LPO P2RX4 3353/4885SLC1A3 4780/4885SLC1A2 4802/4885
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 P2RX4 3934/4885SLC1A3 3779/4885SLC1A2 4125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.