Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 5/20 | 0.43 |
| ▸ | NOS3 | P29474 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25095247 | 0.80 | S100B (0.41) | MAPTNOS1NOS3CYP3A4KDM4E | |
| SCHEMBL1734530 | 0.77 | NOS1 (0.45) | MAPTHTR3EHTR3BPLAUHTR3A | |
| SCHEMBL1734529 | 0.77 | NOS1 (0.45) | MAPTHTR3EHTR3BPLAUHTR3A | |
| SCHEMBL10153370 | 0.74 | PTGS2 (0.46) | MAPTHTR3EHTR3BPLAUHTR3A | |
| SCHEMBL23644553 | 0.74 | NOS1 (0.43) | MAPTHTR3EHTR3BPLAUHTR3A | |
| SCHEMBL14395758 | 0.73 | HTR3E (0.52) | HTR3EHTR3BPLAUHTR3AHTR3D | |
| SCHEMBL1547498 | 0.73 | HTR3E (0.52) | MAPTHTR3EHTR3BPLAUHTR3A | |
| SCHEMBL19322071 | 0.73 | NOS3 (0.44) | PLAUPTGS2PTGS1NOS1NOS3 | |
| SCHEMBL28964176 | 0.72 | PTGS2 (0.60) | MAPTPTGS2PTGS1CYP1A2CYP3A4 | |
| SCHEMBL23084247 | 0.72 | NOS3 (0.45) | MAPTNOS1NOS3CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237952-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC PRODUCTION OF HIGHLY BRANCHED AMORPHOUS POLYOLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044317-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC PRODUCTION OF HIGHLY BRANCHED AMORPHOUS POLYOLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-21 | — | — | WO | disclosed |