SCHEMBL7628010

SCHEMBL7628010

[CH2]C[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640554 0.71 CALM1 (0.32) CALM1ALDH1A1
SCHEMBL416584 0.71 TP53 (0.41) CALM1ALDH1A1
SCHEMBL5881375 0.70 ALDH1A1 (0.36) ALDH1A1
SCHEMBL8992232 0.69 CALM1 (0.43) CALM1ALDH1A1
SCHEMBL415334 0.67 TP53 (0.38) ALDH1A1
SCHEMBL9745993 0.67 TRPA1 (0.31) ALDH1A1
SCHEMBL671215 0.65 TAAR1 (0.34) ALDH1A1
SCHEMBL6781919 0.65 ALDH1A1 (0.40) CALM1ALDH1A1
SCHEMBL6781917 0.65 ALDH1A1 (0.35) CALM1ALDH1A1
SCHEMBL114778 0.64 LTA4H (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6455458-B1 HIGH MOLECULAR WEIGHT POLYOLEFIN; GROUP 4 TRANSITION METAL COMPLEXES HAVING A BIDENTATE ANCILLARY LIGAND SYSTEM OF ONE CYCLOPENTADIENYL GROUP BOUND TO THE TRANSITION METAL AND A GROUP 15 OR GROUP 16 ATOM COVALENTLY BOUND THROUGH A BRIDGING EXXONMOBIL CHEMICAL PATENTS INC. 2002-09-24 US disclosed
EP-1097161-A1 TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-09 EP disclosed
WO-2000002891-A1 TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2000-01-20 WO disclosed